Ders Detayları
| Code | Name | Type | Year | Semester | ECTS |
| 703001052014 | Physics and Biophysics | Seçmeli | 1 | 1 | 3.00 |
Objectives of the Course
Explanation of structure and function of organisms with physical laws and rules
Name of Lecturer(s)
Öğr. Gör. Serdar Sedat IŞIK
Learning Outcomes
| 1 | Explain structure of living organisms and genesis hierarchy. |
| 2 | Discuss researching living organisms with physical techniques. |
| 3 | Realize biophysical techniques. on molecular biology. |
| 4 | Describe hypothesis, law and rules that effect on function of biological systems |
| 5 | Explain the definition of biophysics and explain the relationship between physics and biophysics |
Mode of Delivery
Öğr. Gör. Serdar Sedat IŞIK
Prerequisites and co-requisities
None
Recommended Optional Programme Components
None
Course Contents
Introduction to biophysics, basic concepts, biological internal environment.Chemical bonds, molecular hierarchyBiophysical properties of water as living environmentpH and buffer systems, regulation of pH at organism level, biomolecules in biological internal environment Structure functions of biomolecules. Lipids and carbohydratesProteins, structure function relationships in hemoglobin sample Structural changes that disrupt hemoglobin function Nucleic acids, structure and types Definition of radioactivity, measurement methods of radioactivity, effect of radioactivity on cell, application of radioactivity in medicine- Beam biophysics, absorption, sparkle, sparkle spectrophotometer, nuclear magnetic resonanceIntroduction to bioenergetics, concepts and definitions, principles of cellular energy transfer Thermodynamic rules for biological systemsThe concept of free energy and entropy, principles of energy transfer Cell respiration, aerobic formation of ATP in mitochondriaBiological works (biosynthesis, muscle contraction, active conduction)Membrane message of molecules from bioenergetic point of view Membrane potentials, electrical equivalent circuits and models Action PotentialsCentral dogma of molecular biology DNA Mapping DNA sequence analysis Regulation of the expression of hereditary knowledge DNA repair Formation and repair of mutations Molecular basis of hereditary diseasesTranscriptionProtein synthesis and protein synthesis
Weekly Detailed Course Contents
| 1 | Introduction of biophysics, basic structure of organisms, chemical bonds, molecular hierarchy. |
| 2 | Biophysical properties of water, pH, buffer system. |
| 3 | Structure and function of biomolecules. Lipids and carbohydrates. |
| 4 | Proteins, relation of structure and function in the example of hemoglobin. Changes on structure of hemoglobin that disturb function. |
| 5 | Nucleic acids, structure and types |
| 6 | Radioactivity, measurement of radioactivıty, effect of radioactivity on cell |
| 7 | midterm exam week |
| 8 | midterm exam week |
| 9 | Biophysics of light, spectrophotometer |
| 10 | Radioactivity in medicine, NMR |
| 11 | Membrane potential, action potential |
| 12 | Biological works (Biosynthesis, muscle contraction, active transport), Thermodynamics, free energy, entropy |
| 13 | Biomechanics-1 |
| 14 | Biomechanics-2 |
| 15 | final exam week |
| 16 | final exam week |
Recommended or Required Reading
Course Notes
Assessment Methods and Criteria
| Yarıyıl (Yıl) İçi Etkinlikleri | 40 |
| Yarıyıl (Yıl) Sonu Etkinlikleri | 60 |
| 100 |
Language of Instruction
Turkish
Work Placement(s)
None
Workload Calculation
| Activities | Count | WORKLOAD (hours) | TOTAL WORKLOAD (hours) |
|---|---|---|---|
| Ara Sınav | 1 | 1 | 1 |
| Final Sınav | 1 | 1 | 1 |
| 1 | 1 | 1 | |
| Derse Katılım | 12 | 2 | 24 |
| 6 | 1 | 6 | |
| Soru-Yanıt | 6 | 1 | 6 |
| 11 | 1 | 11 | |
| Bireysel Çalışma | 8 | 2 | 16 |
| Ara Sınav İçin Bireysel Çalışma | 6 | 2 | 12 |
| Final Sınavı içiin Bireysel Çalışma | 6 | 2 | 12 |
| 90 |